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Yukako Ito Selected Research

Neoplasms (Cancer)

11/2023Mobilization of Circulating Tumor Cells after Short- and Long-Term FOLFIRINOX and GEM/nab-PTX Chemotherapy in Xenograft Mouse Models of Human Pancreatic Cancer.
3/2023A Pharmacokinetic-Pharmacodynamic Model Predicts Uracil-tegafur Effect on Tumor Shrinkage and Myelosuppression in a Colorectal Cancer Rat Model.
2/2020Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in rats.
1/2018Pharmacokinetic and toxicodynamic evaluation of oxaliplatin-induced neuropathy and hematological toxicity in rats.
6/2013Pharmacokinetic/pharmacodynamic modeling of 5-fluorouracil by using a biomarker to predict tumor growth in a rat model of colorectal cancer.
1/2013Pre-therapeutic assessment of plasma dihydrouracil/uracil ratio for predicting the pharmacokinetic parameters of 5-fluorouracil and tumor growth in a rat model of colorectal cancer.
10/2012Small nuclear size of Merkel cell tumors is a useful indicator of poor prognosis.

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Yukako Ito Research Topics

Disease

15Colorectal Neoplasms (Colorectal Cancer)
10/2023 - 01/2013
7Neoplasms (Cancer)
11/2023 - 10/2012
3Infections
01/2021 - 11/2016
3Type 2 Diabetes Mellitus (MODY)
01/2017 - 08/2016
2Peripheral Nervous System Diseases (PNS Diseases)
02/2024 - 12/2023
2Pancreatic Neoplasms (Pancreatic Cancer)
12/2023 - 11/2023
2Acute Kidney Injury (Acute Renal Failure)
10/2023 - 12/2021
2Sepsis (Septicemia)
06/2022 - 05/2020
2Renal Insufficiency (Renal Failure)
12/2021 - 08/2009
2Hyperalgesia
09/2020 - 01/2018
2Dyslipidemias (Dyslipidemia)
05/2020 - 12/2009
2Hypersensitivity (Allergy)
01/2017 - 11/2012
2Obesity
03/2013 - 12/2009
1Circulating Neoplastic Cells
11/2023
1Chronic Renal Insufficiency
10/2023
1Reperfusion Injury
10/2023
1Neoplasm Metastasis (Metastasis)
12/2020
1Inflammation (Inflammations)
05/2020
1Skin Diseases (Skin Disease)
01/2018
1Body Weight (Weight, Body)
08/2017
1Escherichia coli Infections
06/2016
1Thrombocytopenia (Thrombopenia)
01/2015
1Lichen Planus (Lichen Ruber Planus)
11/2012
1Migraine Disorders (Migraine)
12/2011
1Ischemia
08/2009
1Diabetes Mellitus
11/2008
1HIV Infections (HIV Infection)
11/2008
1Hypoglycemia (Reactive Hypoglycemia)
03/2008
1Necrosis
03/2006

Drug/Important Bio-Agent (IBA)

12Fluorouracil (Carac)FDA LinkGeneric
03/2023 - 01/2013
7Oxaliplatin (Eloxatin)FDA LinkGeneric
02/2024 - 01/2018
6ProdrugsIBA
10/2023 - 01/2018
5UracilIBA
03/2023 - 01/2013
5Capecitabine (Xeloda)FDA Link
01/2022 - 01/2018
4PlatinumIBA
02/2024 - 01/2018
4Biomarkers (Surrogate Marker)IBA
10/2023 - 01/2013
4Glucose (Dextrose)FDA LinkGeneric
01/2018 - 08/2016
4SodiumIBA
01/2018 - 08/2016
4Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
10/2013 - 01/2013
3TegafurIBA
10/2023 - 10/2018
3dihydrouracilIBA
10/2013 - 01/2013
2GemcitabineFDA Link
12/2023 - 11/2023
2130-nm albumin-bound paclitaxelIBA
12/2023 - 11/2023
2arbekacinIBA
06/2022 - 01/2021
2VancomycinFDA LinkGeneric
06/2022 - 01/2021
2AcetoneIBA
09/2020 - 01/2018
2Azithromycin (Zithromax)FDA LinkGeneric
05/2020 - 11/2016
2Antineoplastic Agents (Antineoplastics)IBA
02/2020 - 01/2015
2Indicators and Reagents (Reagents)IBA
10/2012 - 03/2006
2HIV Protease InhibitorsIBA
12/2009 - 11/2008
2Nelfinavir (Viracept)FDA Link
12/2009 - 11/2008
1folfirinoxIBA
11/2023
1Linezolid (Zyvox)FDA Link
06/2022
1Anti-Infective Agents (Microbicides)IBA
06/2022
1DaptomycinFDA Link
06/2022
1Irinotecan (Camptosar)FDA LinkGeneric
01/2022
1Anti-Bacterial Agents (Antibiotics)IBA
05/2020
1(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA
05/2020
1Erythromycin (Erycette)FDA LinkGeneric
05/2020
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
05/2020
1MacrolidesIBA
05/2020
1Clarithromycin (Biaxin)FDA LinkGeneric
05/2020
1SymportersIBA
01/2018
1Sodium-Glucose Transporter 2 InhibitorsIBA
01/2018
11,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA
01/2017
1polyarginineIBA
01/2017
1CanagliflozinIBA
10/2016
16- ((4- ethylphenyl)methyl)- 3',4',5',6'- tetrahydro- 6'- (hydroxymethyl)spiro(isobenzofuran- 1(3H),2'- (2H)pyran)- 3',4',5'- triolIBA
08/2016
1sultamicillin (ampicillin-sulbactam)FDA LinkGeneric
06/2016
1Ampicillin (Omnipen)FDA LinkGeneric
06/2016
1Atazanavir Sulfate (Reyataz)FDA Link
03/2013
1ZincIBA
11/2012
1Cyclosporine (Ciclosporin)FDA LinkGeneric
08/2009
1Cytochrome P-450 CYP3AIBA
08/2009
1Streptozocin (Streptozotocin)FDA Link
11/2008
1AlbuminsIBA
11/2008
1Insulin (Novolin)FDA Link
03/2008
1Tacrolimus (Prograf)FDA LinkGeneric
03/2006
1SteroidsIBA
03/2006
1Prednisolone (Predate)FDA LinkGeneric
03/2006
1GlucocorticoidsIBA
03/2006

Therapy/Procedure

8Drug Therapy (Chemotherapy)
12/2023 - 01/2018
2Drug Tapering
12/2021 - 08/2019
1Combination Drug Therapy (Combination Chemotherapy)
10/2023
1Punctures
06/2022
1Ligation
06/2022
1Transplantation
12/2020
1Intraperitoneal Injections
12/2020
1Adjuvant Chemotherapy
10/2018
1Intravenous Administration
08/2017
1Therapeutics
12/2011